Database : HANSEN
Search on : HANSENIASE TUBERCULOIDE/PATOL [Subject descriptor]
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Id:19766
Author:Job, Charles K; Path, FRC.
Title:Nerve damage in leprosy.
Source:Int J Lepr;57(2):532-539, June 1989. .
Descriptors:Hanseníase Dimorfa/compl
Hanseníase Dimorfa/patol
Hanseníase Virchowiana/compl
Hanseníase Virchowiana/patol
Hanseníase Tuberculóide/compl
Hanseníase Tuberculóide/patol
Hanseníase/compl
Hanseníase/patol
Limits:Humanos
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1989/pdf/v57n2/v57n2soalec01.pdf / en
Location:Br191.1


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Id:19762
Author:Mukherjee, Ashok; Misra, Radhey S; Meyers, Wayne M.
Title:An electron microscopic study of lymphatics in the dermal lesions of human leprosy.
Source:Int J Lepr;57(2):506-510, June 1989. ^bilus.
Abstract:The dermal lymphatic vessels in lepromatous and tuberculoid leprosy lesions were studied by light- and electron-microscopy. In the lepromatous patient, lymphatic vessels were seen in both intra- and peri-granulomatous areas. The lymphatic lining cells contained lipid droplets, lysosomes, and numerous pinocytotic vesicles. Cells bearing bacilli were only occasionally seen. In the tuberculoid cases, lymphatic vessels were seen only along the edges of the granulomas and the lining cells were less prominent. Inflammatory cells, both lymphocytes and histiocytes, were found traversing the walls of lymphatic vessels in both groups of patients. The results of the study confirm the continued and increased functioning of the lymphatic drainage system in dermal leprosy lesions, and indicates that it may be a major route for the clearance of lipids from the lipid-rich bacilliferous lesions in the lepromatous patient. The lymphatic pathway appears to be a minor pathway for the dissemination of Mycobacterium leprae in comparison with the blood vascular system^ien.
Descriptors:Hanseníase Virchowiana/microbiol
Hanseníase Virchowiana/patol
Hanseníase Tuberculóide/microbiol
Hanseníase Tuberculóide/patol
Limits:Humanos
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1989/pdf/v57n2/v57n2a09.pdf / en
Location:Br191


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Id:19761
Author:Patnaik, Jaya Krishna; Saha, Prafulla Kumar; Satpathy, Sanjav Kumar; Das, Bhabani Sankar; Bose, Tarit Kumar.
Title:Hepatic morphology in reactional states of leprosy.
Source:Int J Lepr;57(2):499-505, June 1989. ^bilus.
Abstract:Liver function tests and liver biopsies were studied in 23 leprosy patients in reaction and 10 without reaction. The liver biopsies in leprosy patients with reaction showed exudative lesions, epithelioid and tuberculoid granulomas, and foam-cell granulomas. Portal vasculitis was encountered in a few cases. Neutrophilic infiltration into the foam-cell granulomas was seen in a few cases of lepromatous (LL) leprosy with reaction. In six cases of borderline (BL, BB and BT) leprosy with reaction, a spectrum of lesions bearing footprints of exudative lesions were seen evolving into epithelioid-cell granulomas. Foam-cell granulomas and tuberculoid and epithelioid granulomas along with exudative lesions were encountered in two cases on individual biopsy strips. An altered albumin-to-globulin ratio was the chief functional derangement observed in these cases. The spectrum of changes observed in borderline leprosy with reaction could be discrete steps in the evolution of upgrading reaction^ien.
Descriptors:Hanseníase Dimorfa/compl
Hanseníase Dimorfa/patol
Hanseníase Virchowiana/compl
Hanseníase Virchowiana/patol
Hanseníase Tuberculóide/compl
Hanseníase Tuberculóide/patol
Limits:Humanos
Masculino
Feminino
Criança
Adolescente
Adulto
Meia-Idade
Idoso
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1989/pdf/v57n2/v57n2a08.pdf / en
Location:Br191.1


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Id:19760
Author:Rangdaeng, Samreung; Scollard, David M; Suriyannon, Vinai; Smith, Trevor; Thamprasert, Kamthorn; Theetranont, Choti.
Title:Studies of human leprosy lesions in situ using suction induced blisters 1. Cellular components of new, uncomplicated lesions.
Source:Int J Lepr;57(2):492-498, June 1989. ^btab, ^bgraf.
Abstract:The cellular contents of blisters induced by suction over new, uncomplicated leprosy lesions, and in the skin of cured, control patients, have been examined with enzyme- and immuno-histochemical staining over a period of 4 days. The total cellularity of the blisters varied over a wide range, not correlated with the type of leprosy. Mononuclear cells predominated at all times studied, with nearly equal percentages of monocytes and T lymphocytes. The T-helper: suppressor ratio was significantly greater in BT than in BL and LL lesions at 48 hr. Suction blisters offer a painless, quantitative, reproducible, multiple-sampling method for obtaining cells from the cutaneous infiltrates of leprosy for phenotyping or functional analysis^ien.
Descriptors:Hanseníase Dimorfa/patol
Hanseníase Virchowiana/patol
Hanseníase Tuberculóide/patol
Hanseníase/patol
Limits:Humanos
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1989/pdf/v57n2/v57n2a07.pdf / en
Location:Br191.1


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Id:19713
Author:Jayaseelan, Elizabeth; Shariff, Shameem; Rout, Pritilata.
Title:Cytodiagnosis of primary neuritic leprosy.
Source:Int. J. Lepr;67(4):429-434, Dec., 1999. ilus, tab.
Abstract:The diagnosis of primary neuritic leprosy (PNL) and its differentiation from other causes of peripheral neuropathy is difficult since acid-fast bacilli (AFB) smears and skin biopsy are negative from anesthetic areas. A biopsy of the involved nerve is the only conclusive method of diagnosis. Such a biopsy may not necessarily be free of complications when a large nerve is involved. However, fine needle aspiration has in this study proved to be a simple technique to demonstrate inflammation granulomas and AFB from these involved nerves in 18 of the 27 cases suspected to have PNL. The validity of the cytological classification into morphological subtypes may have to be supplemented by a large series of studies. (AU)^ien.
Descriptors:Hanseníase/genet
Hanseníase/patol
Hanseníase Tuberculóide/genet
Hanseníase Tuberculóide/patol
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1999/pdf/v67n4/v67n4a09.pdf / en
Location:BR191.1


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Id:19214
Author:Schujman, Salomon; Carboni, Eduardo A.
Title:Lepra tuberculoide com sindrome de Besnier Boeck Schaumann / Tuberculoid leprosy with syndrome of Besnier Boeck Schaumann
Source:Rev. bras. Leprol;10(2):131-147, jun. 1942. ^bilus.
Abstract:- Los autores presentan un caso de lepra tuberculoide con lesiones cutáneas y viscerales semejantes a las descritas en el Sindrome de Besnier-Boeck-Schaumann (B.B.S.). - Dermatológicamente presenta las manchas eritematosas, los pequeñosy grandes nódulos descritos por Boeck en su Sarcoide y placas infiltradas cianóticas, semejantes a las del lupus pernio. La sensibilidad a nivel de la mayoría de esas lesiones está alterada y la investigación del Mycobacterium leprae en las mismas resultó positiva. - El estudio histológico evidencia la típica estructura sarcoídica con infiltraciones nodulares en dermis y hipodermis a gran predominio epiteliode con escasos linfocitos y ausencia de células gigantes;pero lo característico en este caso es la alteración de los nervios reflejada por la invasión del infiltrado en los mismos y por la neuritis intersticial, hecho al que asignan valor diferencial entre el sarcoide leproso y no leproso. - Como lesiones extracutáneas y otros caracteres que justifican calificarlo como un caso de sindrome de B.B.S., describen: la adenopatía, las lesiones pulmonares, tumefacciones articulares, la monositosis y la anergia tubeculínica. - La adenopatia en ese caso es inguinal y axilar doble, pero los ganglios mayores, (algunos del tamaño de una avallana grande) se encuentran en la axila. El estudio histológico de uno de esos ganglios revela abundantes y tipicos nidos epiteliodes. La búsqueda del Mycobacterium leprae dió resultados positivos y la inoculación al cabayo de un triturado de ese ganglio fué completamente negativa. - La radiografia del pulmón revela imágenes idénticas a las que se observan en el Sarcoide de Boeck, como ser: Adenopatia hiliar y nódulos parenquimatosos, bien delimitados a punto de partida hiliar (Prof. Bonila). - No se encontraron radiológicamente las lesiones óseas descritas por Jungling (Osteitis cistoides y en parrilla, pero en cambio se constataron clinicamente marcadas tumefacciones periarticulares de muñecas, rodilla y t^ien.
Descriptors:Hanseníase Tuberculóide/patol
Hanseníase Tuberculóide/fisiopatol
Sarcoidose/fisiopatol
Limits:Humanos
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/brasleprol/1942/pdf/v10n2/v10n2a01.pdf / pt
Location:BR191.1


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Id:19131
Author:Godoy, Sylvia.
Title:Lepra tuberculóide figurada com muco nasal esporadicamente positivo / Tuberculoid leprosy figured with nasal mucus sporadically positive
Source:Rev. bras. Leprol;21(3):203-206, set. 1953. .
Descriptors:Hanseníase Tuberculóide/patol
Hanseníase Tuberculóide/fisiopatol
Mucosa Nasal/microbiol
Mucosa Nasal/secr
Limits:Humanos
Feminino
Adulto
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/1953/PDF/v21n3/v21n3a03.pdf / pt
Location:BR191.1


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Id:19063
Author:Azulay, R. D; Andrade, Lygia Madeira Cezar.
Title:Indices de positividade bacterioscópica nos tipos histológicos indeterminado e tuberculóide encontrados na lepra / Indices of positive gram stain in the histological types found indeterminate and tuberculoid leprosy
Source:Rev. bras. Leprol;20(1):20-21, mar. 1952. .
Abstract:Os AA. estudaram, sob o ponto de vista bacterioscópico, 1.096 fragmentos de pele de doentes de lepra das formas I, T e Tr, encontrando os seguintes resultados: Forma Indeterminada - 5,2% de positividade. Forma Tuberculoide quiescente - 0,37% de positividade - Forma Tuberculóide reacional (típica e limitante) - 52,1% de positividade. Chama-se a atenção para a importância da Tuberculóide reacional em saúde pública.(AU)^ipt.
Descriptors:Hanseníase Tuberculóide/genet
Hanseníase Tuberculóide/imunol
Hanseníase Tuberculóide/patol
Hanseníase Tuberculóide/fisiopatol
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/1952/PDF/v20n1/v20n1a02.pdf / pt
Location:BR191.1


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Id:19050
Author:Campos, Nelson de Souza.
Title:Reação leprótica: reação leprótica tuberculóide e lepra tuberculóide reacional / Leprous reaction: tuberculoid leprous reaction and reactive tuberculoid leprosy
Source:Rev. bras. Leprol;19(4):249-254, dez. 1951. .
Descriptors:Hanseníase Tuberculóide/epidemiol
Hanseníase Tuberculóide/patol
Hanseníase Tuberculóide/fisiopatol
Hanseníase Tuberculóide/reabil
Hanseníase Tuberculóide/terap
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/1951/PDF/v19n4a04.pdf / pt
Location:BR191.1


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Id:18985
Author:Páteo Junior, José Duarte do.
Title:Da lepra inicipiente na vigilância sanitária dos fócos domiciliares (Estudo dos comunicantes) / Leprosy inicipiente in surveillance of outbreaks home (Study of contacts)
Source:Rev. bras. Leprol;17(4):249-263, dez. 1949. ^btab.
Descriptors:Hanseníase Tuberculóide/patol
Hanseníase Tuberculóide/fisiopatol
Hanseníase Tuberculóide/reabil
Limits:Humanos
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/1949/PDF/v17n4/v17n4a03.pdf / pt
Location:BR191.1


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Id:18973
Author:Pupo, João de Aguiar.
Title:Evolução da leprose / Evolution mite
Source:Rev. bras. Leprol;17(3):157-174, set. 1949. ^bilus, ^btab, ^bgraf.
Descriptors:Hanseníase Dimorfa/compl
Hanseníase Dimorfa/patol
Hanseníase Dimorfa/fisiopatol
Hanseníase Virchowiana/compl
Hanseníase Virchowiana/patol
Hanseníase Virchowiana/fisiopatol
Hanseníase Tuberculóide/compl
Hanseníase Tuberculóide/patol
Hanseníase Tuberculóide/fisiopatol
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/1949/PDF/v17n3/v17n3a04.pdf / pt
Location:BR191.1


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Id:18952
Author:Budiansky, Estella.
Title:Comportamento da alergia tuberculínica em filhos de leprosos, após calmetização / Behavior of tuberculin allergy in children of lepers, after calmetization
Source:Rev. bras. Leprol;17(1):27-30, mar. 1949. .
Descriptors:Hanseníase Tuberculóide/imunol
Hanseníase Tuberculóide/patol
Hanseníase Tuberculóide/fisiopatol
Limits:Humanos
Masculino
Feminino
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/revistas/1949/PDF/v17n1/v17n1a03.pdf / pt
Location:BR191.1


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Id:18396
Author:Carayon, A
Title:Bilan de recherches physiopathologiques sur la nevrite lepreuse: 1-role de la temperature, des microtraumatismes par elongation ou subluxation nerveuse et de la striction canalaire ?-
Source:s.l; s.n; 1977. 18p p. ilus.
Abstract:(Role of temperature, microtraumatisms by elongation or subluxation and canalar stricture.) Cold has a slight aggravating effect on leprosy which is observed in some countries as Iran, South Russia, North India and the Andean cordillera. The subluxation of the ulnar nerve has facilitating effect in the development of the neuritic damage in a limited number of patients. The elongation is important for the production of the ulnar neuritis. The canalar stricture is a major factor causing nerve damage in leprosy. It explains the segmentary localization of the principal damages of the leprous nerves in the proximal areas situated above the tunnels. Intraneural hypertension appears first and is responsible for the swelling of the nerve which gets entraped inside the tunnel. A circulus viciosus is, then, created which maintains and aggravates the intraneural hypertension.
Descriptors:HANSENIASE DIMORFA/compl
HANSENIASE DIMORFA/imunol
HANSENIASE DIMORFA/microbiol
HANSENIASE DIMORFA/patol
HANSENIASE DIMORFA/fisiopatol
HANSENIASE VIRCHOWIANA/compl
HANSENIASE VIRCHOWIANA/imunol
HANSENIASE VIRCHOWIANA/microbiol
HANSENIASE VIRCHOWIANA/patol
HANSENIASE VIRCHOWIANA/fisiopatol
HANSENIASE TUBERCULOIDE/compl
HANSENIASE TUBERCULOIDE/imunol
HANSENIASE TUBERCULOIDE/microbiol
HANSENIASE TUBERCULOIDE/patol
HANSENIASE TUBERCULOIDE/fisiopatol
NEURITE/etiol
SINDROMES DE COMPRESSAO NERVOSA/etiol
 NERVOS PERIFERICOS/les
 NERVOS PERIFERICOS/patol
 NERVOS PERIFERICOS/fisiopatol
Limits:HUMANO
Location:BR191.1; 00508/s


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Id:18383
Author:Bhatia, M. S; Chandra, R; Kamra, A
Title:Delusional parasitosis in leprosy (Correspondence) ..-
Source:s.l; s.n; 2002. 2 p. .
Descriptors:HANSENIASE TUBERCULOIDE/diag
HANSENIASE TUBERCULOIDE/patol
ILUSOES/etiol
HANSENIASE TUBERCULOIDE/clas
 HANSENIASE TUBERCULOIDE/compl
 DOENCAS PARASITARIAS/psicol
Limits:HUMANO
Location:BR191.1; 09309/s


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Id:18378
Author:Velasco, Felix
Title:Tuberculoid leprosy - its transformation into lepromatous type ..-
Source:s.l; s.n; 1940. 16 p. ilus, tab.
Abstract:A brief review of the contradictory opinions of different authors as to the nature and the place of tuberculoid cases of leprosy in the evolution and pathogenesis of the disease is presented. Mention is also made of their failure to agree on what could be generally considered as the esential histological features of this condition. A case of tuberculoid leprosy which has undergone transformation into a lepromatous-type case within six years of observation is presented. This case report together with the clinical, bacteriological and histological studies of other authors seem to agree with the opinion of Manalang that tuberculoid leprosy is a stage in the evolution of leprosy, not immutable as assert by Schujman. That such transformation among adult tuberculoid cases is rare because they represent the filtered resistant ones or benign infections, is indicated. The need for continued follow-up and life-long study of contact children born of leper parents in institutions is indispensable if we are to know the evolution of leprosy. (AU).
Descriptors:HANSENIASE VIRCHOWIANA/compl
HANSENIASE VIRCHOWIANA/diag
HANSENIASE VIRCHOWIANA/microbiol
HANSENIASE VIRCHOWIANA/patol
HANSENIASE TUBERCULOIDE/compl
HANSENIASE TUBERCULOIDE/diag
HANSENIASE TUBERCULOIDE/microbiol
HANSENIASE TUBERCULOIDE/patol
HANSENIASE/clas
HANSENIASE/compl
HANSENIASE/diag
HANSENIASE DIMORFA/compl
 HANSENIASE DIMORFA/diag
 MYCOBACTERIUM LEPRAE/citol
 MYCOBACTERIUM LEPRAE/imunol
 MYCOBACTERIUM LEPRAE/patogen
Limits:RELATO DE CASO
Location:BR191.1; 00661/s


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Id:18214
Author:Gadoth, N; Bechar, M; Kushnir, M; Davidovitz, S; Sandbank, U
Title:Somatosensory and autonomic neuropathy as the only manifestation of long standing leprosy ..-
Source:s.l; s.n; 1979. 7 p. ilus.
Abstract:The clinical and neuropathological findings an a patient with "neuritic" leprosy are described. In this rare form of leprosy, skin changes are only minimal or absent anf the diagnosis can be established only by nerve biopsy (AU).
Descriptors:HANSENIASE TUBERCULOIDE/clas
HANSENIASE TUBERCULOIDE/compl
HANSENIASE TUBERCULOIDE/diag
HANSENIASE TUBERCULOIDE/patol
NEURITE/compl
NEURITE/diag
NEURITE/etiol
NEURITE/patol
CORNEA/metab
 CORNEA/microbiol
 NERVO SURAL/anat
 NERVO SURAL/les
 NERVO SURAL/microbiol
 NERVO SURAL/patol
 NERVO SURAL/cirurg
Limits:RELATO DE CASO
Location:BR191.1; 09203/s


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Id:18213
Author:Mathew, D; Kishore, B. Nanda ; Shwethadri, G. K; Sukumar; Shetty, N. J
Title:An evaluation of clinical and histopathological status in paucibacillary leprosy patients after completion of sixed duration therapy ..-
Source:s.l; s.n; 2004. 8 p. tab.
Abstract:The presente study was carried out involving 25 patients with paucibacillary leprosy who attended the outpatient department of dermatology of Father Muller's Medical College Hospital during the period January 2001 to March 2002. All the patients were examined clinically and histopathologically at the beginning and at the end of six months of MDT and relevant data recorded. Clinicopathological correlation with histopathological classification before MDT was 72% and 68% at the end of MDT in our study. At the end of treatment 4 (16%) cases were clinically active and 8 (32%) were histopathologically active. The study showed that active cases were siginificantly reduced as a result of MDT, both clinically and histopatologically. The histopathological activity that outlasts MDT may be due to the bacillary fragments that persist; but clincial activity coupled with histopathological activity seen in 2 patients at the end of 6 months of MDT was possibly an indicator of relapse and these patients and similar others need to be follewed up for a longer duration. Is this study, resolution of granuloma and clinical activity after completion of MDT were assessed (AU).
Descriptors:HANSENIASE TUBERCULOIDE/compl
HANSENIASE TUBERCULOIDE/patol
HANSENIASE TUBERCULOIDE/fisiopatol
HANSENIASE TUBERCULOIDE/terap
RESULTADO DE TRATAMENTO
HANSENOSTATICOS/admin
HANSENOSTATICOS/farmacol
HANSENOSTATICOS/uso terap
QUIMIOTERAPIA COMBINADA
HANSENIASE/clas
 HANSENIASE/diag
 HANSENIASE/terap
Limits:HUMANO
Location:BR191.1; 08999/s


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Id:18202
Author:Walsh, Douglas S; Lane, Joshua E; Abalos, Rodolfo M; Myint, Khin Saw Aye
Title:Tunel and limited immunophenotypic analysis of apoptosis in paucibacillary leprosy lesions ..-
Source:s.l; s.n; 2004. 5 p. ilus.
Abstract:Some mycobacterial infections, such as tuberculosis, are characterized by apoptosis in infected or by-stander mononuclear immune cells. For localized (paucibacillary, PB) and diseminated (multibacillary, MB) leprosy, characterized by polarized Thl-like vs, Th2-like immune responses, respectivelly little is known about lesional apoptosis. We analyzed sections of paraffin-embedded, untreated leprosy lesions from 21 patients by an indirect immunofluorescent terminal deoxynucleotide-transferase-mediated dUTP-digoxigenin nick end labeling (TUNEL) assay. Some TUNEL (+) PB sections were then reacted with phycoerythein-conjugated (red)antibodies against T cells, monocytes, or antigen-presenting (Langerhans) cells. TUNEL (+) bodies were detected in 9 of 16 PB lesions (56%) and in 1 of 5 MB lesions (20%). Some TUNELL (+) bodies in PB disease were CD3+ (T cell), as well as CD4+ (T-helper) or cd8+ (T-cytotoxic) Apoptosis characterizes PB and MB leprosy lesions and may be more freqeunt in PB disease. In PB disease, some TUNEL (+) bodies may derive from T cells (AU).
Descriptors:HANSENIASE DIMORFA/imunol
HANSENIASE VIRCHOWIANA/imunol
HANSENIASE TUBERCULOIDE/imunol
HANSENIASE/imunol
IMUNOHISTOQUIMICA/util
MYCOBACTERIUM LEPRAE/patogen
HANSENIASE/patol
HANSENIASE DIMORFA/patol
HANSENIASE VIRCHOWIANA/patol
HANSENIASE TUBERCULOIDE/patol
APOPTOSE/imunol
 APOPTOSE/fisiol
 IMUNOHISTOQUIMICA/normas
 BIOPSIA/util
Limits:HUMANO
Location:BR191.1; 09200/s


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Id:17511
Author:Belone, Andrea de Faria Fernandes
Title:Hanseniase na faixa tuberculoide: estudo comparativo entre manifestacoes torpidas e reacionais atraves de avaliacoes de antigenos micabcterianos e de parametros representativos de hipersensibilidade medida por celulas, em biopsias cutaneas ?-
Source:Botucatu; s.n; 2004. 94 p. ilus, tab.
Thesis:Present for Universidade Estadual Paulista. Faculdade de Medicina de Botucatu presented for the degree Doutor.
Descriptors:HANSENIASE TUBERCULOIDE/microbiol
HANSENIASE TUBERCULOIDE/patol
ANTIGENOS
CITOCINAS
CELULAS/imunol
Limits:RELATO DE CASO
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/teses/BELONE_ANDREA/PDF/BELONE_ANDREA.pdf / pt
Location:BR191.1; WC335.102.34, B418h


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Id:17498
Author:Opromolla, Diltor Vladimir Araujo
Title:Considerações em torno da hanseníase tuberculóide reacional ?-
Source:Bauru; s.n; s.d. 4p p. .
Descriptors:HANSENIASE TUBERCULOIDE/compl
HANSENIASE TUBERCULOIDE/diag
HANSENIASE TUBERCULOIDE/epidemiol
HANSENIASE TUBERCULOIDE/hist
HANSENIASE TUBERCULOIDE/patol
Limits:RELATO DE CASO
Location:BR191.1; 00274/s



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