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Id: | 19760
| Author: | Rangdaeng, Samreung; Scollard, David M; Suriyannon, Vinai; Smith, Trevor; Thamprasert, Kamthorn; Theetranont, Choti. | Title: | Studies of human leprosy lesions in situ using suction induced blisters 1. Cellular components of new, uncomplicated lesions.
| Source: | Int J Lepr;57(2):492-498, June 1989. ^btab, ^bgraf.
| Abstract: | The cellular contents of blisters induced by suction over new, uncomplicated leprosy lesions, and in the skin of cured, control patients, have been examined with enzyme- and immuno-histochemical staining over a period of 4 days. The total cellularity of the blisters varied over a wide range, not correlated with the type of leprosy. Mononuclear cells predominated at all times studied, with nearly equal percentages of monocytes and T lymphocytes. The T-helper: suppressor ratio was significantly greater in BT than in BL and LL lesions at 48 hr. Suction blisters offer a painless, quantitative, reproducible, multiple-sampling method for obtaining cells from the cutaneous infiltrates of leprosy for phenotyping or functional analysis^ien.
| Descriptors: | Hanseníase Dimorfa/patol Hanseníase Virchowiana/patol Hanseníase Tuberculóide/patol Hanseníase/patol
| Limits: | Humanos
| Electronic Medium: | http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1989/pdf/v57n2/v57n2a07.pdf / en
| Location: | Br191.1 |
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